Pharmaceutical

Pharmaceutical packaging must protect product integrity above all, and the proven formats are glass bottles and vials, plastic and aluminum tubes, airless dispensers, fine mist sprayers, and aerosols. The right format depends on the dosage form, route of administration, and stability requirements. Evergreen supplies these formats for pharmaceutical and nutraceutical applications, with 3rd-party compliance testing provided.

Pharmaceutical packaging must comply with FDA regulations in the US — including container closure system requirements and USP standards for materials like glass — and equivalent EMA requirements in Europe. Documentation must demonstrate the packaging protects product identity, strength, quality, and purity. Evergreen provides 3rd-party compliance testing to verify adherence to product and industry requirements.

Pharmaceutical packaging suppliers should operate under documented quality management systems such as ISO 9001 or ISO 15378, the standard specific to primary pharmaceutical packaging materials. Brands should verify certifications against the specific component being sourced, since requirements differ by product and market. Evergreen supports qualification with 3rd-party compliance testing and audit documentation.

Quality control systems are critical because a packaging defect — a contaminated component, an out-of-spec dimension, a misprinted label — can compromise patient safety and trigger a recall of the drug product itself. Inspection must happen at the source with full lot traceability. Evergreen audits every facility across 165 quality management metrics, with QC engineers onsite at all productions.

Pharmaceutical glass is classified by USP type, with Type I borosilicate used for sensitive injectables and Type III soda-lime glass common for oral liquids and solid dosage forms. Amber glass adds UV protection for light-sensitive formulations. Evergreen supplies pharmaceutical glass in flint, amber, green, and cobalt blue colors.

Regulatory labeling — dosage information, lot codes, expiration dating, and warnings — is applied through pressure-sensitive labels, direct silkscreen printing, or offset printing, with the method chosen for legibility and permanence. Direct printing eliminates label application as a failure point. Evergreen offers advanced decoration and printing capabilities suited to regulatory labeling requirements.

Airless dispensers suit preservative-sensitive topical formulations because they prevent air ingress and contamination during use, while dropper bottles provide precise dosing for oral and topical liquids. Both formats support dosing accuracy, a regulatory consideration in its own right. Evergreen supplies airless systems and dropper bottles for pharmaceutical applications.

Nutraceuticals are typically packaged in plastic bottles and jars with induction-sealed closures, pouches for powders and gummies, and tins or paper tubes for premium positioning. Requirements are less stringent than for drugs but still demand food-grade compliance and tamper evidence. Evergreen supplies nutraceutical formats with FDA-compliance testing provided.